BDBM387191 1-(4-((5-chloro-4-((2-(cyclopropylsulfonyl)octahydrocyclopenta[c]pyrrol-5-yl)amino)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)propan-2-ol::US9938257, Example 44

SMILES CC(O)Cn1cc(Nc2ncc(Cl)c(NC3CC4CN(CC4C3)S(=O)(=O)C3CC3)n2)cn1

InChI Key InChIKey=XMSFPGDGANKHJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387191   

TargetAurora kinase A(Human)
Calitor Sciences

US Patent
LigandPNGBDBM387191(1-(4-((5-chloro-4-((2-(cyclopropylsulfonyl)octahyd...)
Affinity DataIC50: 5nMAssay Description:Aurora-A:Kinase assays can be performed by measurement of incorporation of γ-33P ATP into immobilized myelin basic protein (MBP). High binding w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

TargetAurora kinase B(Human)
Calitor Sciences

US Patent
LigandPNGBDBM387191(1-(4-((5-chloro-4-((2-(cyclopropylsulfonyl)octahyd...)
Affinity DataIC50: 1nMAssay Description:Aurora-B:Kinase assays can be performed by measurement of incorporation of γ-33P ATP into immobilized myelin basic protein (MBP). High binding w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent