BDBM387190 5-((5-chloro-2-((1-(2-hydroxy-2-methylpropyl)-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)amino)-N-cyclopropylhexahydrocyclopenta[c]pyrrole-2(1H)-sulfonamide::US9938257, Example 43

SMILES CC(C)(O)Cn1cc(Nc2ncc(Cl)c(NC3CC4CN(CC4C3)S(=O)(=O)NC3CC3)n2)cn1

InChI Key InChIKey=VBRVXGOYKOISKC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387190   

TargetAurora kinase A(Human)
Calitor Sciences

US Patent
LigandPNGBDBM387190(5-((5-chloro-2-((1-(2-hydroxy-2-methylpropyl)-1H-p...)
Affinity DataIC50: 9nMAssay Description:Aurora-A:Kinase assays can be performed by measurement of incorporation of γ-33P ATP into immobilized myelin basic protein (MBP). High binding w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
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