BDBM387189 5-((5-chloro-2-((1-(2-hydroxypropyl)-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)amino)-N-cyclopropylhexahydrocyclopenta[c]pyrrole-2(1H)-carboxamide::US9938257, Example 41

SMILES CC(O)Cn1cc(Nc2ncc(Cl)c(NC3CC4CN(CC4C3)C(=O)NC3CC3)n2)cn1

InChI Key InChIKey=VINDCRMTKZGIAF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387189   

TargetAurora kinase A(Human)
Calitor Sciences

US Patent
LigandPNGBDBM387189(5-((5-chloro-2-((1-(2-hydroxypropyl)-1H-pyrazol-4-...)
Affinity DataIC50: 19nMAssay Description:Aurora-A:Kinase assays can be performed by measurement of incorporation of γ-33P ATP into immobilized myelin basic protein (MBP). High binding w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
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