BDBM387069 1-(4-Methoxyphenyl)-N5-(1-(3-oxomorpholino)piperidin-4-yl)-1H-pyrazole-3,5-dicarboxamide::US9938272, Example 15

SMILES COc1ccc(cc1)-n1nc(cc1C(=O)NC1CCN(CC1)N1CCOCC1=O)C(N)=O

InChI Key InChIKey=ORDFJBYOBIZZSP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387069   

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandPNGBDBM387069(1-(4-Methoxyphenyl)-N5-(1-(3-oxomorpholino)piperid...)
Affinity DataKi:  30nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
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LigandPNGBDBM387069(1-(4-Methoxyphenyl)-N5-(1-(3-oxomorpholino)piperid...)
Affinity DataKi:  30nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent