BDBM385712 4-[7- (cyclopropyl- methoxy)- [1,2,4]triazolo[1,5- a]pyridin-5- yl]benzonitrile::US10287286, Example 118

SMILES N#Cc1ccc(cc1)-c1cc(OCC2CC2)cc2ncnn12

InChI Key InChIKey=JCSJIJVKUYLANF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 385712   

TargetProlyl hydroxylase EGLN2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM385712(4-[7- (cyclopropyl- methoxy)- [1,2,4]triazolo[1,5-...)
Affinity DataIC50: 54nMAssay Description:The IC50 values for the PHD1 enzyme (residues 1-407) were determined by mixing increasing amounts of a compound of the invention with a fixed amount ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2020
Entry Details
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