BDBM385633 US10287292, Compound 1.026::US11059825, Compound 1.026

SMILES O=C(N[C@H]1CCN(C1)c1nccn2ccnc12)c1csc(n1)N1CCC1

InChI Key InChIKey=CECVYDMLQYYSCJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 385633   

TargetAtypical chemokine receptor 3(Human)
Chemocentryx

US Patent
LigandPNGBDBM385633(US10287292, Compound 1.026 | US11059825, Compound ...)
Affinity DataIC50: 500nMAssay Description:In order to more properly assess the binding efficacy of the compounds, radioligand binding assays were carried out in the presence of 100% human ser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
Go to US Patent

TargetAtypical chemokine receptor 3(Human)
Chemocentryx

US Patent
LigandPNGBDBM385633(US10287292, Compound 1.026 | US11059825, Compound ...)
Affinity DataIC50: 500nMAssay Description:In order to more properly assess the binding efficacy of the compounds, radioligand binding assays were carried out in the presence of 100% human ser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
Go to US Patent