BDBM385532 (1R,6S or 1S, 6R)-4- ((S or R)-1-(2-chloro- 6-(1- (trifluoromethyl)cyclo- propyl)benzoyl)-6- (3-methoxyazetidine- 1-carbonyl)-4,5,6,7- tetrahydro-1H- indazol-3-yl)-6- methylcyclohex-3- ene-1-carboxylic acid::US10287272, Example 17D::US10287272, Example 17E::US10689369, Example 17E
SMILES COC1CN(C1)C(=O)C1CCc2c(C1)n(nc2C1=CC[C@H]([C@@H](C)C1)C(O)=O)C(=O)c1c(Cl)cccc1C1(CC1)C(F)(F)F
InChI Key InChIKey=NEGMILSFVWIQIL-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 385532
Affinity DataIC50: 1nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair