BDBM385387 (E)-3-Fluoro-2-[[2-(4-methoxy-1-piperidyl)pyrimidin-5-yl]oxymethyl]prop-2-en-1-amine, Dihydrochloride::US10287270, Example 3::US10464928, Example 3::US10793552, Example 3

SMILES COC1CCN(CC1)c1ncc(OC\C(CN)=C\F)cn1

InChI Key InChIKey=BAFWVBYUHNFONP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 385387   

TargetAmine oxidase [copper-containing] 3(Human)
Eli Lilly

US Patent
LigandPNGBDBM385387((E)-3-Fluoro-2-[[2-(4-methoxy-1-piperidyl)pyrimidi...)
Affinity DataIC50: 12nMAssay Description:Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo assay kit from Promega (V1402). Test compounds (wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Eli Lilly

US Patent
LigandPNGBDBM385387((E)-3-Fluoro-2-[[2-(4-methoxy-1-piperidyl)pyrimidi...)
Affinity DataIC50: 12nMAssay Description:Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo assay kit from Promega (V1402). Test compounds (wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Eli Lilly

US Patent
LigandPNGBDBM385387((E)-3-Fluoro-2-[[2-(4-methoxy-1-piperidyl)pyrimidi...)
Affinity DataIC50: 12nMAssay Description:Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo assay kit from Promega (V1402). Test compounds (wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent