BDBM385383 6-(2-((2,6-Dimethylphenyl)amino)-1H-imidazol-1-yl)-N-(4-(4-ethylpiperazin-1-yl)phenyl)pyrimidin-4-amine::US10287268, Compound I-1::US10975058, Compound I-1
SMILES CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)-n2ccnc2Nc2c(C)cccc2C)cc1
InChI Key InChIKey=AOFHNVJLLKVQCD-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 385383
Affinity DataIC50: 338nMAssay Description:In some experiments, inhibitory activities of the compounds described herein against select protein kinases were determined as IC50 values (e.g., IC5...More data for this Ligand-Target Pair
Affinity DataIC50: 111nMAssay Description:In some experiments, inhibitory activities of the compounds described herein against select protein kinases were determined as IC50 values (e.g., IC5...More data for this Ligand-Target Pair
Affinity DataIC50: 338nMAssay Description:This buffer consisted of 50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 1 mg ml−1 bovine serum albumin and 0.1% (vol/vol) 2-mercaptoethanol.10× Concentra...More data for this Ligand-Target Pair
Affinity DataIC50: 111nMAssay Description:This buffer consisted of 50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 1 mg ml−1 bovine serum albumin and 0.1% (vol/vol) 2-mercaptoethanol.10× Concentra...More data for this Ligand-Target Pair