BDBM385023 (S)-5-(2-methoxy-5-(2H-tetrazol-5-yl)benzyl)-6-methyl-N4-(1-(methylthio)heptan-3-yl)pyrimidine-2,4-diamine ::US10287253, Example 34

SMILES CCCC[C@@H](CCSC)Nc1nc(N)nc(C)c1Cc1cc(ccc1OC)-c1nn[nH]n1

InChI Key InChIKey=BFBWZTNFFNNPGJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 385023   

TargetToll-like receptor 7(Human)
Apros Therapeutics

US Patent
LigandPNGBDBM385023((S)-5-(2-methoxy-5-(2H-tetrazol-5-yl)benzyl)-6-met...)
Affinity DataEC50: <100nMAssay Description:HEK-Blue TLR7 cells were purchased from Invivogen (San Diego, Calif.). The following description was taken from the product information sheet."HEK-Bl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
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