BDBM3847 1-Phenylbenzimidazole deriv. 64::5-Substituted 1-Phenylbenzimidazole 6::5-methoxy-1-phenyl-1H-1,3-benzodiazole

SMILES COc1ccc2n(cnc2c1)-c1ccccc1

InChI Key InChIKey=BMNCXCJXZKZJII-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 3847   

TargetPlatelet-derived growth factor receptor beta(Human)
University of Auckland

LigandPNGBDBM3847(5-Substituted 1-Phenylbenzimidazole 6 | 5-methoxy-...)
Affinity DataIC50: 430nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Auckland

LigandPNGBDBM3847(5-Substituted 1-Phenylbenzimidazole 6 | 5-methoxy-...)
Affinity DataIC50: 430nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandPNGBDBM3847(5-Substituted 1-Phenylbenzimidazole 6 | 5-methoxy-...)
Affinity DataIC50: 2.20E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandPNGBDBM3847(5-Substituted 1-Phenylbenzimidazole 6 | 5-methoxy-...)
Affinity DataIC50: 2.20E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

LigandPNGBDBM3847(5-Substituted 1-Phenylbenzimidazole 6 | 5-methoxy-...)
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2005
Entry Details Article
PubMed