BDBM384276 US10280184, Example F.1.42

SMILES C=CC(=O)N1CC(C1)c1cc(Nc2cc3COCCn3n2)c2ncnn2c1

InChI Key InChIKey=VVGXLKHTWSUNCY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384276   

TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM384276(US10280184, Example F.1.42)
Affinity DataIC50: 100nMAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent