BDBM384254 US10280184, Example F.1.19

SMILES C=CC(=O)N1CCC(C1)c1cn2ncnc2c(Nc2ccc(nc2)N2CCOCC2)n1

InChI Key InChIKey=MPYVTJYHNIRRCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384254   

TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM384254(US10280184, Example F.1.19)
Affinity DataIC50: 550nMAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent