BDBM384109 US10280167, Example 54

SMILES CN(C)CCOc1ccc(Cn2c3nc(nc(N)c3[nH]c2=O)-c2nc(c[nH]2)C2CC2)cn1

InChI Key InChIKey=VSFPFXHMYPOJKU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384109   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM384109(US10280167, Example 54)
Affinity DataEC50:  50nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent