BDBM383957 (1R,2R)-2-(2-((3,5-dichloro-1H- pyrazol-1-yl)methyl)-8-methyl-4-oxo- 4H-pyrido[1,2-a]pyrimidin-6- yl)cyclopropanecarbonitrile::US10280165, Example 57

SMILES Cc1cc([C@@H]2C[C@H]2C#N)n2c(c1)nc(Cn1nc(Cl)cc1Cl)cc2=O

InChI Key InChIKey=VDFTUZVXDISNQN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383957   

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383957((1R,2R)-2-(2-((3,5-dichloro-1H- pyrazol-1-yl)methy...)
Affinity DataEC50:  222nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent