BDBM383944 2-[2-[[3-chloro-5- (trifluoromethyl)pyrazol-1- yl]methyl]-8-methyl-4-oxo- pyrido[1,2-a]pyrimidin-6- yl]cyclopropanecarbonitrile::US10280165, Example 43

SMILES Cc1cc(C2CC2C#N)n2c(c1)nc(Cn1nc(Cl)cc1C(F)(F)F)cc2=O

InChI Key InChIKey=HVBJXKGBBYZTEF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383944   

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383944(2-[2-[[3-chloro-5- (trifluoromethyl)pyrazol-1- yl]...)
Affinity DataEC50:  269nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent