BDBM383940 (1S,2S)-2-[2-[[5-chloro-3- (trifluoromethyl)pyrazol-1- yl]methyl]-8-methyl-4-oxo- pyrido[1,2-a]pyrimidin-6- yl]cyclopropanecarbonitrile::US10280165, Example 39

SMILES Cc1cc([C@H]2C[C@@H]2C#N)n2c(c1)nc(Cn1nc(cc1Cl)C(F)(F)F)cc2=O

InChI Key InChIKey=XSISCWOKUQLCCR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383940   

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383940((1S,2S)-2-[2-[[5-chloro-3- (trifluoromethyl)pyrazo...)
Affinity DataEC50:  951nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent