BDBM383479 N-[[(1S,8R)-5-(2,6- difluorophenyl)-11,11-dimethyl- 3,4- diazatricyclo[6.2.1.02,7]undeca- 2,4,6-trien-1-yl]methyl]-N-ethyl- 5-hydroxy-pyrimidine-2- carboxamide::US10280144, Compound 194

SMILES CCN(C[C@@]12CC[C@@H](c3cc(nnc13)-c1c(F)cccc1F)C2(C)C)C(=O)c1ncc(O)cn1

InChI Key InChIKey=PFBCJKJFPQVPHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383479   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM383479(N-[[(1S,8R)-5-(2,6- difluorophenyl)-11,11-dimethyl...)
Affinity DataIC50: 2nMAssay Description:Consumable Supplier and product code GFB Unifilter plates Perkin Elmer 6005177 3-[(3- Sigma C5070 Cholamidopropyl)dimethylammonio]- 1-propanesulfonat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
US Patent