BDBM38321 6-(3,4-dimethoxyphenyl)-3-(2-furanyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole::6-(3,4-dimethoxyphenyl)-3-(2-furyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole::6-(3,4-dimethoxyphenyl)-3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole::MLS000037114::SMR000042111::cid_661498

SMILES COc1ccc(cc1OC)-c1nn2c(nnc2s1)-c1ccco1

InChI Key InChIKey=CDPQLJPWAPUNKT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 38321   

TargetDiphosphomevalonate decarboxylase(Streptococcus pneumoniae D39)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM38321(cid_661498 | 6-(3,4-dimethoxyphenyl)-3-(furan-2-yl...)
Affinity DataIC50: 2.35E+5nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM38321(cid_661498 | 6-(3,4-dimethoxyphenyl)-3-(furan-2-yl...)
Affinity DataIC50: 2.48E+4nMAssay Description:Inhibition of hexa-His-tagged recombinant human SIRT1 expressed in Escherichia coli BL21(DE3) using AMC-labeled Arg-His-Lys-Lys(ac) as substrate asse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM38321(cid_661498 | 6-(3,4-dimethoxyphenyl)-3-(furan-2-yl...)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human N-terminal His-tagged dCTPase 1 expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2019
Entry Details Article
PubMed