BDBM383196 US10278968, Compound 724::US10793535, Cmpd ID 724

SMILES CC(C)(C)OC(=O)Nc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4cccc(OC(F)(F)F)c4)nn3)s2)n1

InChI Key InChIKey=GTBLMEKCKSPWPW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 383196   

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM383196(US10278968, Compound 724 | US10793535, Cmpd ID 724)
Affinity DataIC50: 140nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
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TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM383196(US10278968, Compound 724 | US10793535, Cmpd ID 724)
Affinity DataIC50: 140nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent