BDBM382123 6-(4-(2,4-difluorophenoxy)piperidin-1-yl)-5-(isopropylamino)-3-morpholinopyrazine-2-carbonitrile::US10000468, Example 32::US10273225, Example 32

SMILES CC(C)Nc1nc(N2CCOCC2)c(nc1N1CCC(CC1)Oc1ccc(F)cc1F)C#N

InChI Key InChIKey=UUPPUNREICFVIO-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 382123   

TargetG-protein coupled receptor 6(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM382123(US10000468, Example 32 | 6-(4-(2,4-difluorophenoxy...)
Affinity DataEC50:  2.35E+4nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetG-protein coupled receptor 6(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM382123(US10000468, Example 32 | 6-(4-(2,4-difluorophenoxy...)
Affinity DataEC50:  2.35E+4nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
Go to US Patent