BDBM382048 2-[1-(2-methyl-1- phenylpropyl)imidazol-4- yl]pyridine-4-carboxylic acid::US10273222, Example 108

SMILES CC(C)C(c1ccccc1)n1cnc(c1)-c1cc(ccn1)C(O)=O

InChI Key InChIKey=VJLABPNSGBCXOH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 382048   

TargetLysine-specific demethylase 5A(Human)
Celgene Quantscel Research

US Patent
LigandPNGBDBM382048(2-[1-(2-methyl-1- phenylpropyl)imidazol-4- yl]pyri...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent

TargetLysine-specific demethylase 2B(Human)
Celgene Quantscel Research

US Patent
LigandPNGBDBM382048(2-[1-(2-methyl-1- phenylpropyl)imidazol-4- yl]pyri...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent

TargetLysine-specific demethylase 5B(Human)
Celgene Quantscel Research

US Patent
LigandPNGBDBM382048(2-[1-(2-methyl-1- phenylpropyl)imidazol-4- yl]pyri...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent

TargetLysine-specific demethylase 4A(Human)
Celgene Quantscel Research

US Patent
LigandPNGBDBM382048(2-[1-(2-methyl-1- phenylpropyl)imidazol-4- yl]pyri...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2A was determined in 384-well plate format under the following reaction conditions: 2 nM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quantscel Research

US Patent
LigandPNGBDBM382048(2-[1-(2-methyl-1- phenylpropyl)imidazol-4- yl]pyri...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent