BDBM381929 US10273211, Compound 19

SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)cc[n+]([O-])c2cc1OC

InChI Key InChIKey=FKJJTKYQXXLFPS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 381929   

TargetHepatocyte growth factor receptor(Human)
Exelixis

US Patent
LigandPNGBDBM381929(US10273211, Compound 19)
Affinity DataIC50: 275nMAssay Description:Kinase Activity was measured and profiled by EMD Millipore according to the Kinase Profiler Service Assay Protocols Protocol Guide Volume 57. The res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Exelixis

US Patent
LigandPNGBDBM381929(US10273211, Compound 19)
Affinity DataIC50: 275nMAssay Description:Kinase Activity was measured and profiled by EMD Millipore according to the Kinase Profiler Service Assay Protocols Protocol Guide Volume 57. The res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Exelixis

US Patent
LigandPNGBDBM381929(US10273211, Compound 19)
Affinity DataIC50: 2.75E+3nMAssay Description:Kinase Activity was measured and profiled by EMD Millipore according to the Kinase Profiler Service Assay Protocols Protocol Guide Volume 57. The res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
Go to US Patent

TargetAurora kinase B(Human)
Exelixis

US Patent
LigandPNGBDBM381929(US10273211, Compound 19)
Affinity DataIC50: 2.75E+3nMAssay Description:Kinase Activity was measured and profiled by EMD Millipore according to the Kinase Profiler Service Assay Protocols Protocol Guide Volume 57. The res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
Go to US Patent