BDBM381894 3-(3-(2,2-Dimethyl-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)-2,3-dihydro-1H-inden-5-yl)-2,2-dimethyl-5-(4-propyl-1H-1,2,3-triazol-1-yl)pentanoic Acid, Trifluoroacetic Acid Salt::US10272095, Example 65

SMILES CCCc1cn(CCC(c2ccc3CCC(N4Cc5ccccc5OC(C)(C)C4)c3c2)C(C)(C)C(O)=O)nn1

InChI Key InChIKey=NTMXBWFZPJUXID-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381894   

TargetNAD(P)H dehydrogenase [quinone] 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM381894(3-(3-(2,2-Dimethyl-2,3-dihydrobenzo[f][1,4]oxazepi...)
Affinity DataEC50:  55nMAssay Description:NAD(P)H:quinone oxidoreductase 1 (NQO1), also called DT diaphorase, is a homodimeric FAD-containing enzyme that catalyzes obligatory NAD(P)H-dependen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent