BDBM38114 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-7-(1-methyl-1H-pyrrol-2-yl)-N-(phenylsulfonyl)-1H-indole-2-carboxamide::US10093640, Example 101::US10844032, Example 101

SMILES Cc1cc(OCCCc2c([nH]c3c(cccc23)-c2cccn2C)C(=O)NS(=O)(=O)c2ccccc2)cc(C)c1Cl

InChI Key InChIKey=KQJQTKNTEWUEEN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 38114   

LigandPNGBDBM38114(US10093640, Example 101 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Compound affinity was measured using a fluorescence polarization anisotropy competition assay. Anisotropy measurements were carried out in 384-well, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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LigandPNGBDBM38114(US10093640, Example 101 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
Go to US Patent