BDBM380611 2-Amino-8-(5-piperazin-1-ylsulfonyl-3-pyridyl)-N,N-dipropyl-3H-1-benzazepine-4-carboxamide::US9890124, 20

SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)-c1cncc(c1)S(=O)(=O)N1CCNCC1

InChI Key InChIKey=ZYIUHZMDBPZUPA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 380611   

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380611(US9890124, 20 | 2-Amino-8-(5-piperazin-1-ylsulfony...)
Affinity DataEC50:  17nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
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TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380611(US9890124, 20 | 2-Amino-8-(5-piperazin-1-ylsulfony...)
Affinity DataEC50:  5.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent