BDBM380595 (4-(((trans)-4-(dimethylamino)cyclohexyl)amino)quinazolin-6-yl)methanol::US9926330, 8-1

SMILES CN(C)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(CO)cc12

InChI Key InChIKey=KHNXYBJYGRLBAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380595   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM380595(US9926330, 8-1 | (4-(((trans)-4-(dimethylamino)cyc...)
Affinity DataIC50: 29nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent