BDBM380565 US9926330, 2-18::trans-N-(6- methylquinazolin-4-yl)-N'- (tetrahydro-2H-pyran-4- ylmethyl)cyclohexane-1,4- diamine

SMILES Cc1ccc2ncnc(N[C@H]3CC[C@@H](CC3)NCC3CCOCC3)c2c1

InChI Key InChIKey=JXWFJDCCGUZYQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380565   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM380565(trans-N-(6- methylquinazolin-4-yl)-N'- (tetrahydro...)
Affinity DataIC50: 46nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent