BDBM380101 5-chloro-1-methyl-N-[4- (4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]-1H-indole-2- carboxamide::US9926282, Example 96

SMILES Cn1c(cc2cc(Cl)ccc12)C(=O)Nc1ccc(cc1)-c1n[nH]c(=O)c2ccccc12

InChI Key InChIKey=URRNTYNAOZRIEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 380101   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM380101(5-chloro-1-methyl-N-[4- (4-oxo-3,4- dihydrophthala...)
Affinity DataIC50: 100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM380101(5-chloro-1-methyl-N-[4- (4-oxo-3,4- dihydrophthala...)
Affinity DataIC50: 550nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent