BDBM37950 US10093631, Compound Formula (Ik)

SMILES Oc1[nH]c(=O)[nH]c(=O)c1C(=O)Nc1ccncc1

InChI Key InChIKey=AKVPULQDSJJKMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 37950   

TargetSolute carrier family 22 member 12(Human)
Acquist

US Patent
LigandPNGBDBM37950(US10093631, Compound Formula (Ik))
Affinity DataIC50: 5.30E+3nMAssay Description:URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM37950(US10093631, Compound Formula (Ik))
Affinity DataIC50: 1.43E+4nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
Go to US Patent