BDBM379476 US10266550, Compound 11k

SMILES CCCCCNc1c(F)cc2c3c1oc1cc(N)ccc1n3cc(C(O)=O)c2=O

InChI Key InChIKey=VFFQJQUSOGNZSJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 379476   

TargetDNA topoisomerase 1(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM379476(US10266550, Compound 11k)
Affinity DataIC50: 1.56E+4nMAssay Description:The relaxation activity of E. coli topoisomerase I was assayed in a buffer containing 10 mM Tris-HCl, pH 8.0, 50 mM NaCl, 0.1 mg/mL gelatin, and 0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
Go to US Patent