BDBM379465 US10266550, Compound 10b

SMILES OC(=O)c1cn2c3ccc(cc3oc3c(N4CCNCC4)c(F)cc(c23)c1=O)[N+]([O-])=O

InChI Key InChIKey=HXLWFRAVXNLMFV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 379465   

TargetDNA topoisomerase 1(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM379465(US10266550, Compound 10b)
Affinity DataIC50: 3.90E+3nMAssay Description:The relaxation activity of E. coli topoisomerase I was assayed in a buffer containing 10 mM Tris-HCl, pH 8.0, 50 mM NaCl, 0.1 mg/mL gelatin, and 0.5 ...More data for this Ligand-Target Pair
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Date in BDB:
2/7/2020
Entry Details
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