BDBM379046 4-({2-[1-(2- fluorobenzyl)- 1H-indazol-3-yl]- 5-(2- hydroxyethoxy) pyrimidin-4- yl}amino)pyridine- 3-carboxamide::US10266548, Example 13-5

SMILES NC(=O)c1cnccc1Nc1nc(ncc1OCCO)-c1nn(Cc2ccccc2F)c2ccccc12

InChI Key InChIKey=SMDQWFRSTBPJBD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 379046   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM379046(4-({2-[1-(2- fluorobenzyl)- 1H-indazol-3-yl]- 5-(2...)
Affinity DataIC50: 6.5nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
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