BDBM378960 2-[1-(2,6- difluoro-3- methoxybenzyl)- 1H-indazol-3-yl]- 5-methoxy-N- (pyridin-4- yl)pyrimidin-4- amine::US10266548, Example 2-4-1

SMILES COc1ccc(F)c(CN(\N=C\c2ncc(OC)c(Nc3ccncc3)n2)c2ccccc2)c1F

InChI Key InChIKey=XCZLFLKRAMORNY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378960   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM378960(US10266548, Example 2-4-1 | 2-[1-(2,6- difluoro-3-...)
Affinity DataIC50: 4.5nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
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