BDBM378915 2-[1-(6-chloro-2-fluoro-3-methylbenzyl)-1H-indazol-3-yl]-5-methoxy-N-(pyridin-4-yl)pyrimidin-4-amine::US10266548, Example 2-1-1

SMILES COc1cnc(nc1Nc1ccncc1)-c1nn(Cc2c(Cl)ccc(C)c2F)c2ccccc12

InChI Key InChIKey=UCOFWWYBTJWSPL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378915   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM378915(US10266548, Example 2-1-1 | 2-[1-(6-chloro-2-fluor...)
Affinity DataIC50: 2.60nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
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