BDBM378882 US10266535, Compound 45

SMILES CC(C)[C@@H](N)C(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12

InChI Key InChIKey=DASBULWGLYMECT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 378882   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Hefei Institutes of Physical Science, Chinese Academy of Sciences

US Patent
LigandPNGBDBM378882(US10266535, Compound 45)
Affinity DataIC50: 32nMAssay Description:In the experiments of in vitro enzymatic activity, the IC50 values of Compound 33, Compound 30, Compound 14, Compound 20, Compound 22, Compound 23, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Hefei Institutes of Physical Science, Chinese Academy of Sciences

US Patent
LigandPNGBDBM378882(US10266535, Compound 45)
Affinity DataIC50: 260nMAssay Description:In the experiments of in vitro enzymatic activity, the IC50 values of Compound 33, Compound 30, Compound 14, Compound 20, Compound 22, Compound 23, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
Go to US Patent