BDBM378860 US10266535, Compound 20

SMILES Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCN(C1)C(=O)CC#N

InChI Key InChIKey=IQSNQCPIVCYLCJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 378860   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Hefei Institutes of Physical Science, Chinese Academy of Sciences

US Patent
LigandPNGBDBM378860(US10266535, Compound 20)
Affinity DataIC50: 718nMAssay Description:In the experiments of in vitro enzymatic activity, the IC50 values of Compound 33, Compound 30, Compound 14, Compound 20, Compound 22, Compound 23, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Hefei Institutes of Physical Science, Chinese Academy of Sciences

US Patent
LigandPNGBDBM378860(US10266535, Compound 20)
Affinity DataIC50: 114nMAssay Description:In the experiments of in vitro enzymatic activity, the IC50 values of Compound 33, Compound 30, Compound 14, Compound 20, Compound 22, Compound 23, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
Go to US Patent