BDBM37871 6-Ethyl-thieno[2,3-d]pyrimidin-4-ol::6-ethyl-3H-thieno[2,3-d]pyrimidin-4-one::CHEMBL6215::MLS000029626::SMR000009585::cid_645569

SMILES CCc1cc2c(s1)N=CNC2=O

InChI Key InChIKey=GXZAQJCUXCKYKB-UHFFFAOYSA-N

Data  5 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 37871   

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37871(MLS000029626 | 6-Ethyl-thieno[2,3-d]pyrimidin-4-ol...)
Affinity DataIC50: 5.96E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37871(MLS000029626 | 6-Ethyl-thieno[2,3-d]pyrimidin-4-ol...)
Affinity DataIC50: 5.72E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM37871(MLS000029626 | 6-Ethyl-thieno[2,3-d]pyrimidin-4-ol...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro potency against TNF alpha induced expression of intercellular adhesion molecule-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM37871(MLS000029626 | 6-Ethyl-thieno[2,3-d]pyrimidin-4-ol...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular cell adhesion protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM37871(MLS000029626 | 6-Ethyl-thieno[2,3-d]pyrimidin-4-ol...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro potency against TNF alpha induced expression of VCAM-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed