BDBM37864 2-thiophenecarboxylic acid [1-(4-methoxyphenyl)sulfonyl-5-[[oxo(thiophen-2-yl)methyl]amino]-3-pyrazolyl] ester::PC-0095741::PCMD-CC-MCM-27::[1-(4-methoxyphenyl)sulfonyl-5-(thiophen-2-ylcarbonylamino)pyrazol-3-yl] thiophene-2-carboxylate::[1-(4-methoxyphenyl)sulfonyl-5-(thiophene-2-carbonylamino)pyrazol-3-yl] thiophene-2-carboxylate::cid_11834392::thiophene-2-carboxylic acid [1-(4-methoxyphenyl)sulfonyl-5-(2-thenoylamino)pyrazol-3-yl] ester

SMILES COc1ccc(cc1)S(=O)(=O)n1nc(OC(=O)c2cccs2)cc1NC(=O)c1cccs1

InChI Key InChIKey=NTXUGHUVWHRAIZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37864   

TargetCathepsin B(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM37864([1-(4-methoxyphenyl)sulfonyl-5-(thiophene-2-carbon...)
Affinity DataIC50: 3.23E+3nMAssay Description:Human liver cathepsin B (EC 3.4.22.1) is a lysosomal cysteine protease. There has been a recent resurgence of interest in cathepsin B due to research...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay