BDBM377544 US10266493, Example 2FF::US10919858, Example 2FF

SMILES OC(=O)C(F)(F)Sc1ccncc1-c1ccc(C#N)c2ccccc12

InChI Key InChIKey=VPRKREFVYXVNQW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 377544   

TargetSolute carrier family 22 member 12(Human)
Ardea Biosciences

US Patent
LigandPNGBDBM377544(US10266493, Example 2FF | US10919858, Example 2FF)
Affinity DataEC50:  5.25E+3nMAssay Description:HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
Go to US Patent

TargetSolute carrier family 22 member 12(Human)
Ardea Biosciences

US Patent
LigandPNGBDBM377544(US10266493, Example 2FF | US10919858, Example 2FF)
Affinity DataEC50:  6.25E+3nMAssay Description:HEK293 human embryonic kidney cells (ATCC #CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% C02 an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent