BDBM377306 US10265310, Example 59::US10265310, Example 60

SMILES COCCN1CC(NC(=O)Nc2ccc(Cl)cc2)C(CC1=O)c1ccc(OC)cc1F

InChI Key InChIKey=URIVGRCPVSWQRJ-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 377306   

TargetN-formyl peptide receptor 2(Human)
GrÜNenthal

US Patent
LigandPNGBDBM377306(US10265310, Example 60 | US10265310, Example 59)
Affinity DataEC50: <1nMAssay Description:Cryo-vial containing 6×106 cells (hFPR1-Gα15-CHO or hFPR2-Aq-CHO) was thawed in a 37° C. water bath. Cells were suspended in 10 ml of respective...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent

TargetN-formyl peptide receptor 2(Human)
GrÜNenthal

US Patent
LigandPNGBDBM377306(US10265310, Example 60 | US10265310, Example 59)
Affinity DataEC50:  500nMAssay Description:Cryo-vial containing 6×106 cells (hFPR1-Gα15-CHO or hFPR2-Aq-CHO) was thawed in a 37° C. water bath. Cells were suspended in 10 ml of respective...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent

TargetfMet-Leu-Phe receptor(Human)
GrÜNenthal

US Patent
LigandPNGBDBM377306(US10265310, Example 60 | US10265310, Example 59)
Affinity DataEC50:  500nMAssay Description:Cryo-vial containing 6×106 cells (hFPR1-Gα15-CHO or hFPR2-Aq-CHO) was thawed in a 37° C. water bath. Cells were suspended in 10 ml of respective...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent

TargetfMet-Leu-Phe receptor(Human)
GrÜNenthal

US Patent
LigandPNGBDBM377306(US10265310, Example 60 | US10265310, Example 59)
Affinity DataEC50:  500nMAssay Description:Cryo-vial containing 6×106 cells (hFPR1-Gα15-CHO or hFPR2-Aq-CHO) was thawed in a 37° C. water bath. Cells were suspended in 10 ml of respective...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent