BDBM377275 US10265310, Example 21::rac-trans-methyl 2-(5-(3-(4-chlorophenyl)ureido)-4-(4-methoxyphenyl)-2-oxopiperidin-1-yl)acetate

SMILES COC(=O)CN1C[C@H](NC(=O)Nc2ccc(Cl)cc2)[C@H](CC1=O)c1ccc(OC)cc1

InChI Key InChIKey=UANLHVUNOJOIQR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 377275   

TargetN-formyl peptide receptor 2(Human)
GrÜNenthal

US Patent
LigandPNGBDBM377275(US10265310, Example 21 | rac-trans-methyl 2-(5-(3-...)
Affinity DataEC50: <1nMAssay Description:Cryo-vial containing 6×106 cells (hFPR1-Gα15-CHO or hFPR2-Aq-CHO) was thawed in a 37° C. water bath. Cells were suspended in 10 ml of respective...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
Go to US Patent

TargetfMet-Leu-Phe receptor(Human)
GrÜNenthal

US Patent
LigandPNGBDBM377275(US10265310, Example 21 | rac-trans-methyl 2-(5-(3-...)
Affinity DataEC50: <1nMAssay Description:Cryo-vial containing 6×106 cells (hFPR1-Gα15-CHO or hFPR2-Aq-CHO) was thawed in a 37° C. water bath. Cells were suspended in 10 ml of respective...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
Go to US Patent