BDBM377270 US10265310, Example 16::rac-trans-1-(4-chlorophenyl)-3-(4-(4-methoxyphenyl)-1-(tetrahydro-2H-pyran-4-carbonyl)piperidin-3-yl)urea

SMILES COc1ccc(cc1)[C@H]1CCN(C[C@@H]1NC(=O)Nc1ccc(Cl)cc1)C(=O)C1CCOCC1

InChI Key InChIKey=LASKVWGRYRMIOD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 377270   

TargetN-formyl peptide receptor 2(Human)
GrÜNenthal

US Patent
LigandPNGBDBM377270(US10265310, Example 16 | rac-trans-1-(4-chlorophen...)
Affinity DataEC50: <1nMAssay Description:Cryo-vial containing 6×106 cells (hFPR1-Gα15-CHO or hFPR2-Aq-CHO) was thawed in a 37° C. water bath. Cells were suspended in 10 ml of respective...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
Go to US Patent

TargetfMet-Leu-Phe receptor(Human)
GrÜNenthal

US Patent
LigandPNGBDBM377270(US10265310, Example 16 | rac-trans-1-(4-chlorophen...)
Affinity DataEC50: <1nMAssay Description:Cryo-vial containing 6×106 cells (hFPR1-Gα15-CHO or hFPR2-Aq-CHO) was thawed in a 37° C. water bath. Cells were suspended in 10 ml of respective...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
Go to US Patent