BDBM377259 US10265310, Example 5::rac-trans-1-(1-acetyl-4-(2,6-difluoro-4-methoxyphenyl)piperidin-3-yl)-3-(4-chlorophenyl)urea

SMILES COc1cc(F)c([C@H]2CCN(C[C@@H]2NC(=O)Nc2ccc(Cl)cc2)C(C)=O)c(F)c1

InChI Key InChIKey=GLRBBTUYSHHGQI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 377259   

TargetN-formyl peptide receptor 2(Human)
GrÜNenthal

US Patent
LigandPNGBDBM377259(US10265310, Example 5 | rac-trans-1-(1-acetyl-4-(2...)
Affinity DataEC50: <1nMAssay Description:Cryo-vial containing 6×106 cells (hFPR1-Gα15-CHO or hFPR2-Aq-CHO) was thawed in a 37° C. water bath. Cells were suspended in 10 ml of respective...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent

TargetfMet-Leu-Phe receptor(Human)
GrÜNenthal

US Patent
LigandPNGBDBM377259(US10265310, Example 5 | rac-trans-1-(1-acetyl-4-(2...)
Affinity DataEC50:  500nMAssay Description:Cryo-vial containing 6×106 cells (hFPR1-Gα15-CHO or hFPR2-Aq-CHO) was thawed in a 37° C. water bath. Cells were suspended in 10 ml of respective...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent