BDBM377043 US10259818, Example 25::US9944646, Example 25

SMILES CC(c1cc(Cl)c(C)c2c1OCCNC2=O)n1nc(C)c2c(N)ncnc12

InChI Key InChIKey=FTNQUTUTVMYKRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 377043   

LigandPNGBDBM377043(US9944646, Example 25 | US10259818, Example 25)
Affinity DataIC50: 100nMAssay Description:Lipid kinase substrate, phosphoinositol-4,5-bisphosphate (PIP2), are purchased from Echelon Biosciences (Salt Lake City, Utah). PI3K isoforms α,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
Go to US Patent

LigandPNGBDBM377043(US9944646, Example 25 | US10259818, Example 25)
Affinity DataIC50: 100nMAssay Description:[γ-33P]ATP (10mCi/mL) was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Ptd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
Go to US Patent