BDBM377022 US10259818, Example 4::US9944646, Example 4

SMILES CC(c1cc(Cl)c(C)c2CN(CCOc12)C1CN(C1)C(C)=O)n1nc(C)c2c(N)ncnc12

InChI Key InChIKey=VTIKAESNFTYPDQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 377022   

LigandPNGBDBM377022(US9944646, Example 4 | US10259818, Example 4)
Affinity DataIC50: 100nMAssay Description:Lipid kinase substrate, phosphoinositol-4,5-bisphosphate (PIP2), are purchased from Echelon Biosciences (Salt Lake City, Utah). PI3K isoforms α,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
Go to US Patent

LigandPNGBDBM377022(US9944646, Example 4 | US10259818, Example 4)
Affinity DataIC50: 100nMAssay Description:[γ-33P]ATP (10mCi/mL) was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Ptd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
Go to US Patent

LigandPNGBDBM377022(US9944646, Example 4 | US10259818, Example 4)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed