BDBM376998 4-[7-({7-[2-Methoxy-4-trifluoromethylphenyl]-6-methylthieno[3,2-d]pyrimidin-2-yl}amino)-2,3-dihydro-1-benzofuran-4-yl]piperidin-3-ol ::US10259816, Compound 17

SMILES COc1cc(ccc1-c1c(C)sc2cnc(Nc3ccc(C4CCN(CC4O)C(=O)OC(C)(C)C)c4CCOc34)nc12)C(F)(F)F

InChI Key InChIKey=OBMKWZSZHNSHAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376998   

TargetALK tyrosine kinase receptor(Human)
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM376998(US10259816, Compound 17 | 4-[7-({7-[2-Methoxy-4-tr...)
Affinity DataIC50: 2.10nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair
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Date in BDB:
2/7/2020
Entry Details
US Patent