BDBM376920 US10329300, Example 14::US11696917, Example 14::US9920060, 14

SMILES COc1c(NC(=O)c2nn([C@@H]3CCCN(C3)C(=O)C=C)c3ncnc(N)c23)ccc(CC(=O)N(C)C)c1F

InChI Key InChIKey=QSKWWUXRLOLLQJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 376920   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM376920(US9920060, 14 | US10329300, Example 14 | US1169691...)
Affinity DataIC50: 4.60nMAssay Description:For setting the conditions for the method for measuring the in vitro inhibitory activity of a compound against HER2-phosphorylating activity, Profile...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2023
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM376920(US9920060, 14 | US10329300, Example 14 | US1169691...)
Affinity DataIC50: 4.60nMAssay Description:For the inhibitory activity measurement of each compound, the compound of the present invention or staurosporine was first serially diluted with dime...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM376920(US9920060, 14 | US10329300, Example 14 | US1169691...)
Affinity DataIC50: 4.60nMAssay Description:For setting the conditions for the method for measuring the in vitro inhibitory activity of a compound against HER2-phosphorylating activity, Profile...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent