BDBM376843 (R)-(4-fluoro-2-(2H-1,2,3- triazol-2-yl)phenyl)(2-((4-(2- hydroxypropan-2-yl)-5- methyloxazol-2- yl)methyl)piperidin-1- yl)methanone::US9920038, 4

SMILES Cc1oc(C[C@H]2CCCCN2C(=O)c2ccc(F)cc2-n2nccn2)nc1C(C)(C)O

InChI Key InChIKey=KFGRQNJZKWEXFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 376843   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376843(US9920038, 4 | (R)-(4-fluoro-2-(2H-1,2,3- triazol-...)
Affinity DataIC50: 25nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details
Go to US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376843(US9920038, 4 | (R)-(4-fluoro-2-(2H-1,2,3- triazol-...)
Affinity DataIC50: 39nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details
Go to US Patent