BDBM376509 N-(3-cyanobenzyl)-1- fluoro-9H-pyrido[3,4-b] indole-7-carboxamide::US9914740, XIV-30::US9914740, XIV31

SMILES Fc1nccc2c3ccc(cc3[nH]c12)C(=O)NCc1cccc(c1)C#N

InChI Key InChIKey=UFRRATJYGXSMBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 376509   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376509(US9914740, XIV31 | N-(3-cyanobenzyl)-1- fluoro-9H-...)
Affinity DataIC50: 213nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
Go to US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376509(US9914740, XIV31 | N-(3-cyanobenzyl)-1- fluoro-9H-...)
Affinity DataIC50: 1.16nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
Go to US Patent